Ordinal classification tasks are present in a large number of different domains.However, common losses for deep neural networks, such as cross-entropy, do not properly weight the relative ordering between classes.For that reason, many losses have been proposed in the literature, which model the output probabilities as following a unimodal distribut

The uptake of cholesterol from the host is closely linked to the proliferation of pathogenic fungi and protozoa during infection.For some pathogenic fungi, cholesterol uptake is an important strategy for decreasing susceptibility to antifungals that inhibit ergosterol biosynthesis.In this study, we show that Candida glabrata ERG25, which encodes an

In this paper, a refined reference current generation algorithm based on instantaneous power (pq) theory is proposed, for operation of an indirect current controlled (ICC) three-level neutral-point diode clamped (NPC) inverter-based shunt active power filter (SAPF) under non-sinusoidal source voltage conditions.SAPF is recognized as one of the most

T follicular helper (Tfh) cells are a distinct subset of CD4+ T lymphocytes, specialized in B cell help and in regulation of antibody responses.They are required for the generation of germinal center TEA TREE SPRAY reactions, where selection of high affinity antibody producing B cells and development of memory B cells occur.Owing to the fundamental

Pools of mutants of minimal complexity but maximal coverage of genes of interest facilitate screening for genes under selection in a particular environment.We constructed individual deletion mutants in 1,023 Salmonella enterica serovar Typhimurium genes, including almost all genes found in Salmonella but not in related genera.All mutations were con